Health

Research shows that bone marrow cells that crash into spinal joints can ease crippling back pain


A stab that contains tiny bubbles of fat can dispel back pain.

A one-time injection is injected into the spinal joints. It contains a fluid called ExoFlo, which is made up of billions of tiny cells called exosomes – each about the width of a fraction of a human hair. These healing cells, found in the bone marrow, are enclosed in a layer of fat.

Exomes, discovered only in the 1980s, are thought to play an important role in cell repair by reducing inflammation.

They also contain growth factors, which are important for repairing and revitalizing damaged cells throughout the body, and contain genetic material that can improve the way different cells function. .

A one-time injection is injected into the spinal joints.  It contains a fluid called ExoFlo, which is made up of billions of tiny cells called exosomes each about the width of a fraction of a human hair.

A one-time injection is injected into the spinal joints.  It contains a fluid called ExoFlo, which is made up of billions of tiny cells called exosomes each about the width of a fraction of a human hair.

A one-time injection is injected into the spinal joints. It contains a fluid called ExoFlo, which is made up of billions of tiny cells called exosomes – each about a fraction of the width of a human hair.

As well as back pain, these cells are being tested for use in a variety of conditions – from tennis elbow to Crohn’s disease – after scientists at the US company Direct Biologics, have perfected a mass production using bone marrow from a young age. healthy donor.

Once the company has created liquid ExoFlo, it is frozen until needed.

In a study published in the International Journal of Science and Research, some patients who received fat-bubble injections experienced an 80% reduction in back pain within a month of the injection.

Degenerative disc disease, in which the bony discs in the spine degenerate over time, is one of the most common causes of back and neck pain. It is estimated that about 40% of adults age 40 and older have at least one degenerative disc. By age 80, that number rises to 80%.

The main symptom is low-grade chronic pain with episodes of more intense pain, often when nerves become trapped or pinched.

Treatment is with pain medication, physical therapy, and disc replacement surgery. With the new exosome treatment, doctors take a small amount of liquid containing exosome bubbles — about a tenth of a teaspoon — and inject it into a damaged joint in the spine.

This fluid is thought to be able to trigger the healing process by reducing inflammation and promoting the growth of healthy cells to restore the cushioning capacity of the joint.

Doctors at Hudson Medical Center in New York administered ExoFlo liquid to 10 patients who didn’t improve despite other treatment (including painkiller injections) and monitored their progress for a month. after. The results showed an average reduction in back pain scores of 55%, but in some volunteers it went up to 80%.

The stab also helped a patient with a bed ulcer measuring 100 square centimeters (15.5 in sq) that did not respond to surgery. ExoFlo was injected into the wound and within eight weeks it healed, according to the Journal of Surgical Case Reports.

Mike McNicholas, a consultant orthopedic surgeon at Liverpool University Hospital NHS Trust, believes that extra income ‘has huge potential’ and that ‘using them to tackle a huge cushion is proof of that’. He hopes the new trial ‘will confirm that potential and usher in a new era in the treatment of back pain and sciatica’.

Red wine pill can prevent lab life from early menopause

A compound found in red wine could be a new treatment for early menopause.

Resveratrol, which occurs naturally in grape skins, is being prescribed to 150 women in a clinical trial at Nantong University Hospital, China.

All women have premature ovarian failure – a cause of early menopause – which occurs when the ovaries stop working properly before age 40.

It is hoped that a daily dose of 250mg of the wine compound for three months will increase levels of follicle-stimulating hormone, which is important for egg production.

A compound found in red wine could be a new treatment for early menopause.  Resveratrol, which occurs naturally in grape skins, is being prescribed to 150 women in a clinical trial at Nantong University Hospital, China.

A compound found in red wine could be a new treatment for early menopause.  Resveratrol, which occurs naturally in grape skins, is being prescribed to 150 women in a clinical trial at Nantong University Hospital, China.

A compound found in red wine could be a new treatment for early menopause. Resveratrol, which occurs naturally in grape skins, is being prescribed to 150 women in a clinical trial at Nantong University Hospital, China.

Honey can treat depression – that’s the theory behind a trial at the University of Science, Malaysia. It is looking at the use of meliponine honey from bee stings found in tropical countries to treat patients who have not responded to antidepressants.

According to the journal Molecules, honey is rich in phenylalanine, an amino acid needed to make the brain chemicals serotonin and dopamine.

The ‘sticky tape’ solution for chronic snoring

People who snore often sleep with their mouths open, but keeping their mouths shut can help eliminate this problem, according to researchers from the UK and Taiwan, according to researchers from the UK and Taiwan.

They used a medical tape to seal the mouths of 20 snorers at night, forcing them to breathe through their noses while sleeping.

Results published in the journal Healthcare demonstrated that snoring-related sleep disruption was halved in 13 group members.

However, this treatment method is not suitable for people with persistent nasal congestion despite taking medication and should not self-medicate at home.

Life Lab

The story behind the unusual medical discoveries. This week: Covid can transmit as we speak

According to the journal Proceedings of the National Academy of Sciences in June 2020, shining a laser through a dark room helped scientists confirm that Covid-19 can be spread through talking – even among people. no symptoms.

Dr Adriaan Bax, a molecular physicist from the US National Institutes of Health said: Coughs and sneezes produce ‘a lot of respiratory droplets’, but if you don’t have symptoms this won’t happen. out. Thus, we hypothesize that asymptomatic transmission occurs through speaking. ‘

To test this, they used a bright laser in a dark room to observe the droplets emitted when someone spoke. More droplets are emitted than expected, and when they dry out, they stay in the air where they can be inhaled by others.

Small edits

Reduce your calorie intake by a moderate amount. A recent animal study found it may improve health and longevity, and these benefits may extend to humans, reports the journal Immunity. Researchers at Yale also tracked the effects in participants who reduced their calorie intake by 14% for two years or ate as usual. Those who consumed fewer calories had reduced levels of a protein, SPARC, which has been linked to obesity and type 2 diabetes.

Doctor Ink

The tattoos are used for medical purposes. This week: To monitor your heart rate

Monitoring changes in heart rate can provide important clues to the development of heart conditions such as atrial fibrillation (an abnormal heart rhythm).

This usually involves doctors conducting an electrocardiogram (ECG), where electrodes are taped to the chest to measure the heart’s electrical signals. Irregular heart rhythms, however, can come and go, so it usually goes undetected on the ECG.

Now scientists in South Korea have developed an electronic tattoo ink, made of liquid metal and carbon nanotubes, that can monitor those electrical signals throughout the day through the skin, potentially detecting The problem may be undiagnosed.

In the future, the scientists hope to connect a wireless chip to the tattoo so that it can transmit data to a doctor’s computer.

Gout medications absorbed through the skin can reduce side effects

Gout patches can reduce side effects of drug treatment, such as diarrhea, nausea, and upset stomach.

Gout, a form of arthritis, is caused by a buildup of uric acid and usually affects the joints of the big toe. It leads to inflammation and often severe pain.

One of the most effective treatments is colchicine, an anti-inflammatory agent. But some patients struggle to tolerate its side effects. The hope is that the patch, developed at Queen’s University Belfast, can combat this.

It contains the same medication but it penetrates the skin and into the affected joint rather than the intestines like an oral medication, as reported in Biomaterials Science.

Wine may help treat disc-related back pain, according to a study of 67 patients at Opole University Hospital in Poland.

An ethanol gel injected into the degenerated discs resulted in a 66% reduction in pain scores. After six months, 81% of sciatica patients and 74% of those with back pain were no longer taking pain medication.

One theory is that alcohol dehydrates the disc, causing it to contract and reduce pressure on the nerves.

Many patients benefit from diabetes cure

A transplant of islet cells – insulin-producing cells from the pancreas – could cure type 1 diabetes.

But their use is currently limited because it takes three donors to provide enough cells for just one transplant. Cells can also be stored for just two or three days before they deteriorate.

Now, a new way to store islet cells from donors could mean more patients benefiting from the treatment.

The new freezing technique, described in the journal Nature, means the cells can be kept for at least nine months before use.

The team from the University of Minnesota in the US successfully transplanted thawed islet cells into diabetic mice.

Source: | This article originally belonged to Dailymail.co.uk




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