Research published in the journal Biomedicine & Pharmacotherapy says low levels of vitamins B12, B6 and B9 can lead to atherosclerosis, the leading cause of cardiovascular disease and the majority of deaths worldwide. all over the world.
We show that a deficiency of vitamin B, necessary for homocysteine
The degradation, which leads to atherosclerotic transformation of the aorta, leads to accumulation of macrophages and lipids, deterioration of its biomechanical properties and disorganization, the researchers say. collagen/elastin of the aorta in the absence of hypercholesterolemia, the researchers said.
They also add that the combination of vitamin B deficiency and elevated blood cholesterol leads to aortic thickening, decreased aortic water diffusion, increased LDL- or bad cholesterol, and impaired vessel reactivity. blood.
They add that vitamin B deficiency leads to atherosclerotic changes of the aorta even in the absence of hypercholesterolemia and exacerbates atherosclerotic development in its presence.