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Coronavirus Briefing Newsletter – Times of India


COUNT
  • India on Sunday reported 5,076 Covid cases and 11 deaths. Cumulative amount is 4,44,95,359 (47,945 active cases) and 5,28,150 deaths
  • All around the world: More than 608 million cases and more than 6.51 million deaths.
  • Vaccination in India: More than 2.14 billion doses. Worldwide: More than 12.19 billion doses.
TODAY
A new antiviral therapy stops the transmission of Covid
A new antiviral therapy stops the transmission of Covid
  • A team of US scientists has developed a nasal treatment, a dose that not only relieves the symptoms of many Covid variants but also eliminates the virus.
  • In one New research published In the Proceedings of the National Academy of Sciences, the team from the Gladstone Institute in San Francisco showed that this new treatment, called therapeutic interventional particles (TIP), also reduces the amount of virus discharge from infected animals and limit the transmission of the virus.
  • Historically, antivirals and vaccines to limit transmission of respiratory viruses, including SARS-CoV-2, have been a particular challenge for vaccines.
  • “This is a single-dose antiviral drug that not only reduces the symptoms and severity of Covid-19 but also reduces the virus,” said Sonali Chaturvedi, first author of the paper. ” Sonali Chaturvedi, first author of the paper.
  • However, the benefits of TIPs extend beyond their ability to block the virus inside infected cells.
  • Because TIPs reside inside the same cells as the viruses they target, they grow at the same time, working even as new strains of viruses emerge.
  • Initial experiments were performed using the Delta strain of SARS-CoV-2. By day 5, all control animals were still shedding high levels of virus, while virus was undetectable in 4 out of 5 animals treated with TIP.
  • When infected animals are kept in cages with uninfected animals, treating infected animals with TIPs does not completely prevent the transmission of Covid-19.
LET ME KNOW ONE THING
Why Covid-19 symptoms can persist for up to a year
Why Covid-19 symptoms can persist for up to a year
  • In one research published in the magazine of Clinical infectious disease, a team of scientists at Boston-based Harvard Medical School has discovered that the mutant protein of SARS-CoV-2 – the virus that causes Covid-19 disease – can exist in the blood of Covid patients. -19 as long as a year later. infection. The findings support a leading theory among scientists that residual viral particles stimulate an immune system response that causes Covid-19 symptoms.
  • The team studied plasma samples from 63 patients, of which 37 were diagnosed with post-acute sequelae of Covid-19, or persistent Covid-19. The remaining patients recovered from their acute infection. Blood samples were collected at least twice within a year of testing positive.
  • The study detected the presence of the mutated protein in the majority of samples from long-term Covid-19 patients, including samples analyzed even 12 months after acute infection, which They wrote in their paper, “supporting the hypothesis that an active viral reservoir exists in the body. “
  • In one interview arrive The Wall Street JournalDavid Walt, lead author of the study and professor of pathology at Brigham and Women’s Hospital in Boston and Harvard Medical School, says that some long-term Covid-19 patients have high levels of the viral spike protein. as before when sick even a year. after infection.
  • Walt announced that the team is planning to test antiviral drugs like Paxlovid or remdesivir to see if they can help wipe out residual virus and neutralize the spike protein from the blood. are not. Adding that there is a possibility that the usual Covid-19 treatment protocol may not be enough to completely eliminate the viral load in some Covid-19 patients, he said such people may need “exposed longer with these antiviral drugs to completely eliminate” the virus.
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Written by: Rakesh Rai, Sushmita Choudhury, Jayanta Kalita, Prabhash K Dutta, Tejeesh Nippun Singh
Research: Rajesh Sharma



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